Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71847 | 0.82 | KDM4E (0.65) | SMN1; SMN2PTPRCHIF1ACTSLPTPN13 | |
| SCHEMBL1926646 | 0.81 | HIF1A (0.56) | SMN1; SMN2HIF1AKDM4EDEGS1MEN1 | |
| SCHEMBL8333840 | 0.80 | GPR139 (0.45) | SMN1; SMN2HIF1ACTSLMAPTKDM4E | |
| SCHEMBL5944029 | 0.79 | HDAC6 (0.61) | DEGS1CA1MEN1KMT2ALMNA | |
| Methyl Alcohol SCHEMBL6851692 | 0.79 | KDM4E (0.61) | SMN1; SMN2HIF1AMAPTKDM4ESLC22A6 | |
| SCHEMBL16373128 | 0.78 | HPGD (0.51) | SMN1; SMN2HIF1AKDM4EDEGS1MEN1 | |
| SCHEMBL15087815 | 0.78 | HPGD (0.51) | SMN1; SMN2HIF1AKDM4EDEGS1MEN1 | |
| SCHEMBL22030672 | 0.78 | GAA (0.68) | SMN1; SMN2PTPRCHIF1ACTSLPTPN13 | |
| Hippuric Acid SCHEMBL428479 | 0.78 | GAA (0.68) | SMN1; SMN2PTPRCHIF1ACTSLPTPN13 | |
| Hippuric Acid SCHEMBL7486 | 0.78 | GAA (0.68) | SMN1; SMN2PTPRCHIF1ACTSLPTPN13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052921-A1 | CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |