Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166800 | 0.73 | CA1 (0.37) | GBA1CA1CA2CA4 | |
| SCHEMBL17951037 | 0.73 | GBA1 (0.48) | GBA1GAAFUCA1 | |
| SCHEMBL5031412 | 0.72 | MGAM (0.45) | GBA1GAAMGAMSIMGAM2 | |
| SCHEMBL14542252 | 0.72 | MGAM (0.45) | GBA1GAAMGAMSIMGAM2 | |
| SCHEMBL16499829 | 0.71 | GBA1 (0.43) | GBA1 | |
| SCHEMBL20219032 | 0.69 | — | — | |
| Inositol SCHEMBL3835408 | 0.69 | LMNA (0.56) | GBA1GAAMGAMSIMGAM2 | |
| SCHEMBL31344347 | 0.67 | — | — | |
| SCHEMBL13179501 | 0.67 | GLB1 (0.32) | GBA1 | |
| Inositol SCHEMBL5039565 | 0.65 | ALDH1A1 (0.60) | GAAMGAMSIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093732-A1 | LIPID COMPOUNDS AND COMPOSITIONS AND THEIR OPTHALMIC USE | BIOZEP AS (NO) | 2017-06-08 | — | — | WO | disclosed |
| WO-2004089925-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SEMAFORE PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |