Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL1335895 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL5315 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL6928518 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL29355228 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL30320908 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL10462492 | 0.80 | ALDH1A1 (0.50) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL28010966 | 0.80 | ALDH1A1 (0.50) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL4292166 | 0.80 | ALDH1A1 (0.50) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL5358841 | 0.80 | ALDH1A1 (0.55) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL2431603 | 0.80 | ALDH1A1 (0.55) | ALDH1A1NCF1LOXL2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |