Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL27359672 | 0.90 | ALDH1A1 (0.50) | ALDH1A1NCF1MAPTNPC1RAB9A | |
| Biphenyl SCHEMBL29090175 | 0.84 | ALDH1A1 (0.46) | ALDH1A1NCF1MAPTNPC1RAB9A | |
| Quinoxaline SCHEMBL27509310 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NCF1LOXL2MAPTNPC1 | |
| Quinoxaline SCHEMBL8335477 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NCF1LOXL2MAPTNPC1 | |
| Quinoxaline SCHEMBL27373524 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NCF1LOXL2MAPTNPC1 | |
| Quinoxaline SCHEMBL28804078 | 0.83 | ALDH1A1 (0.39) | ALDH1A1NCF1LOXL2MAPTNPC1 | |
| Quinoxaline SCHEMBL30320908 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL6928518 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL5315 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E | |
| Quinoxaline SCHEMBL29355228 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NCF1LOXL2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108138177-B | The combination of Dbait molecule and PARP inhibitor is used for the purposes for the treatment of cancer | 法国居里学院 | 2019-03-19 | — | — | CN | disclosed |
| CN-108138177-A | The combination of Dbait molecules and PARP inhibitor is used for the purposes for the treatment of cancer | 法国居里学院 | 2018-06-08 | — | — | CN | disclosed |
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | TUBA1C, TUBB1, TUBB3 | ALDH1A1 657/4885NCF1 1427/4885LOXL2 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.