Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.48 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335489 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1POLBP4HB | |
| SCHEMBL2058841 | 0.93 | CYP3A4 (0.52) | TSHRLMNAALDH1A1POLBP4HB | |
| SCHEMBL2058839 | 0.93 | CYP3A4 (0.52) | TSHRLMNAALDH1A1POLBP4HB | |
| SCHEMBL1527155 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL7028056 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL16327524 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL230379 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL13435245 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL7028051 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL13461633 | 0.91 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008333-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| US-5750665-A | Preparation of glucosaminyl muramic acid derivatives | ENDOREX CORPORATION | 1998-05-12 | — | — | US | disclosed |