Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.46 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058839 | 1.00 | CYP3A4 (0.52) | CYP3A4MEN1KMT2ATP53CYP2C9 | |
| SCHEMBL8335488 | 0.93 | TSHR (0.52) | CYP3A4MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL8335489 | 0.93 | TSHR (0.52) | CYP3A4MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL8002809 | 0.89 | CYP3A4 (0.46) | CYP3A4MEN1KMT2ATP53CYP2C9 | |
| SCHEMBL2785854 | 0.88 | TSHR (0.52) | KMT2ALMNATSHRCYP2D6P4HB | |
| SCHEMBL16327524 | 0.88 | TSHR (0.54) | KMT2ALMNATSHRCYP2D6P4HB | |
| SCHEMBL13461633 | 0.88 | TSHR (0.54) | KMT2ALMNATSHRCYP2D6P4HB | |
| SCHEMBL230379 | 0.88 | TSHR (0.54) | KMT2ALMNATSHRCYP2D6P4HB | |
| SCHEMBL7028056 | 0.88 | TSHR (0.54) | KMT2ALMNATSHRCYP2D6P4HB | |
| SCHEMBL1527155 | 0.88 | TSHR (0.54) | KMT2ALMNATSHRCYP2D6P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10144849-B2 | Polishing composition and polishing method using the same | FUJIMI INCORPORATED (JP) | 2018-12-04 | — | — | US | disclosed |
| EP-1921086-B1 | ANTITUMOR AGENT | OTSUKA PHARMA CO LTD (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-7968116-B2 | Antitumor agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20100301014-A1 | Polishing Composition and Polishing Method Using the Same | FUJIMI INCORPORATED (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20100292176-A1 | ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2237311-A1 | POLISHING COMPOSITION AND POLISHING METHOD USING THE SAME | FUJIMI INCORPORATED (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20090176970-A1 | Preparation of Thiosugars and Their Use | GLYCOFORM LIMITED (GB) | 2009-07-09 | — | — | US | disclosed |
| EP-1921086-A1 | ANTITUMOR AGENT | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176970-A1 | Preparation of Thiosugars and Their Use | TST, TREH, FUT6 | CYP3A4 1719/4885MEN1 3757/4885KMT2A 4254/4885 |
| US-20100292176-A1 | ANTITUMOR AGENT | CYP46A1, CETP, GYS2 | CYP3A4 1325/4885MEN1 1205/4885KMT2A 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.