Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770939 | 0.88 | NPC1 (0.48) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6769586 | 0.84 | MEN1 (0.51) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7098658 | 0.69 | POLB (0.47) | KMT2AMAPTLMNAPOLBMEN1 | |
| SCHEMBL4979578 | 0.68 | TSHR (0.60) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6768621 | 0.68 | NPC1 (0.68) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4985012 | 0.67 | TSHR (0.58) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6775006 | 0.67 | NPC1 (0.66) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7100142 | 0.66 | SIGMAR1 (0.55) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL24263861 | 0.66 | HSD17B3 (0.46) | HSD17B3KMT2AMAPTLMNAPOLB | |
| SCHEMBL7104842 | 0.66 | RAB9A (0.74) | NPC1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |