Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.86 | ALDH1A1 (0.44) | MAPTTP53SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8051642 | 0.81 | MAPT (0.45) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3743974 | 0.81 | PARP1 (0.40) | MAPTTP53SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL73948 | 0.81 | MAPT (0.36) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7555956 | 0.81 | MAPT (0.39) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672712 | 0.79 | ALDH1A1 (0.36) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672814 | 0.79 | ALDH1A1 (0.36) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL17701156 | 0.79 | MAPT (0.35) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672672 | 0.79 | ALDH1A1 (0.36) | MAPTTP53SMN1; SMN2POLBALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672819 | 0.79 | ALDH1A1 (0.40) | MAPTTP53SMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11209359-A | — | — | None | — | — | JP | disclosed |
| JP-H11209359-A | ALPHA-OXO-1,2,3-BENZOTHIADIAZOLE-7-ACETIC ACID AND ITS PRODUCTION AND PRODUCTION OF 1,2,3-BENZOTHIADIAZOLE-7-CARBOXYLIC ACID USING THE SAME | SUMITOMO SEIKA CHEM CO LTD | 1999-08-03 | — | — | JP | disclosed |