Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336767 | 0.85 | TDP1 (0.33) | USP2ALDH1A1ALOX15TDP1GRIN1 | |
| SCHEMBL8340328 | 0.85 | TP53 (0.33) | ALDH1A1TDP1GRIN1GRIN2B | |
| SCHEMBL2468222 | 0.85 | TDP1 (0.33) | USP2ALDH1A1ALOX15TDP1GRIN1 | |
| SCHEMBL8335901 | 0.80 | — | — | |
| SCHEMBL8334318 | 0.80 | — | — | |
| SCHEMBL8530286 | 0.79 | GRIN1 (0.34) | ALDH1A1GRIN1GRIN2B | |
| SCHEMBL7846561 | 0.78 | GRIN1 (0.38) | ALDH1A1GRIN1GRIN2B | |
| SCHEMBL7847649 | 0.77 | ALDH1A1 (0.32) | ALDH1A1GRIN1GRIN2B | |
| SCHEMBL7070953 | 0.77 | TDP1 (0.34) | USP2ALDH1A1ALOX15TDP1GRIN1 | |
| SCHEMBL8187917 | 0.76 | USP2 (0.38) | USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922727-A | 1-((SUBSTITUTED)CYCLOALK(EN)YLALKYL)-6-((SUB)PHENYL(CARBONYL, SULFIDE, OR OXO))-2,4-PYRIMIDINEDIONE DERIVATIVES HAVING SUPERIOR ANTIVIRAL ACTIVITIES; HIV | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 1999-07-13 | — | — | US | disclosed |