Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846561 | 0.90 | GRIN1 (0.38) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL8340328 | 0.89 | TP53 (0.33) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL7847649 | 0.87 | ALDH1A1 (0.32) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL7076081 | 0.84 | GRIN1 (0.34) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL675171 | 0.82 | KMT2A (0.35) | GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL7847828 | 0.81 | MEN1 (0.33) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL8187917 | 0.80 | USP2 (0.38) | MEN1ALDH1A1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL7846575 | 0.79 | HPD (0.41) | MEN1ALDH1A1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL8393375 | 0.79 | MEN1 (0.33) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL8336258 | 0.79 | USP2 (0.30) | GRIN1GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827498-A1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-03-11 | — | — | EP | disclosed |
| WO-1997030979-A1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-08-28 | — | — | WO | disclosed |