Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 20/20 | 1.00 |
| ▸ | ITGB6 | P18564 | 13/20 | 1.00 |
| ▸ | ITGB1 | P05556 | 2/20 | 1.00 |
| ▸ | ITGA5 | P08648 | 2/20 | 1.00 |
| ▸ | ITGB5 | P18084 | 2/20 | 1.00 |
| ▸ | ITGB8 | P26012 | 2/20 | 1.00 |
| ▸ | ITGA8 | P53708 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6226209 | 0.96 | ITGB3 (0.92) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7835721 | 0.92 | ITGB3 (0.91) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7823462 | 0.91 | ITGB3 (0.91) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6810083 | 0.91 | ITGB3 (0.91) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6226201 | 0.88 | ITGB3 (0.79) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6778717 | 0.88 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL8337383 | 0.88 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6375005 | 0.87 | ITGB3 (0.76) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6229334 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6225649 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199079-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | UNIV SAINT LOUIS (US) | 2020-06-25 | — | — | US | disclosed |
| US-10577330-B2 | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists | SAINT LOUIS UNIVERSITY (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190023663-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY | 2019-01-24 | — | — | US | disclosed |
| US-10035778-B2 | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists | SAINT LOUIS UNIVERSITY (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180072684-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY | 2018-03-15 | — | — | US | disclosed |
| WO-2017117538-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2004060376-A1 | THE R-ISOMER OF BETA AMINO ACID COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPRATION (US) | 2004-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577330-B2 | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists | ITGA2, ITGAL, ITGA5 | ITGB3 17/4885ITGAV 12/4885ITGB6 5/4885 |
| US-20190023663-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | ITGA2, ITGAL, ITGA5 | ITGB3 17/4885ITGAV 12/4885ITGB6 5/4885 |
| US-20200199079-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | ITGA2, ITGAL, ITGA5 | ITGB3 17/4885ITGAV 12/4885ITGB6 5/4885 |
| US-20180072684-A1 | META-AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS PAN INTEGRIN ANTAGONISTS | ITGA2, ITGAL, ITGA5 | ITGB3 17/4885ITGAV 12/4885ITGB6 5/4885 |
| US-10035778-B2 | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists | ITGA2, ITGAL, ITGA5 | ITGB3 17/4885ITGAV 12/4885ITGB6 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.