SCHEMBL8336472

SCHEMBL8336472

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3C(O)C[C@]12C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 7/20 0.74
▸ OSBP P22059 6/20 0.74
▸ OSBP2 Q969R2 3/20 0.74
▸ USP2 O75604 1/20 0.74
▸ LMNA P02545 1/20 0.74
▸ ABCB1 P08183 1/20 0.74
▸ CYP46A1 Q9Y6A2 1/20 0.74
▸ GRIN1 Q05586 6/20 0.63
▸ GRIN2A Q12879 6/20 0.63
▸ NR1H3 Q13133 5/20 0.62
▸ NPC1L1 Q9UHC9 2/20 0.60
▸ CRYAB P02511 1/20 0.60
▸ HMGCR P04035 1/20 0.60
▸ ITGB3 P05106 1/20 0.60
▸ ITGAV P06756 1/20 0.60
▸ SREBF2 Q12772 1/20 0.60
▸ GRIN2B Q13224 5/20 0.59
▸ DHCR24 Q15392 1/20 0.56
▸ EPHA2 P29317 1/20 0.56
▸ RORA P35398 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6387555 1.00 RORC (0.74) RORCOSBPOSBP2USP2LMNA
SCHEMBL6387062 1.00 RORC (0.74) RORCOSBPOSBP2USP2LMNA
SCHEMBL6391972 1.00 RORC (0.74) RORCOSBPOSBP2USP2LMNA
SCHEMBL8336467 1.00 RORC (0.74) RORCOSBPOSBP2USP2LMNA
SCHEMBL6388729 1.00 RORC (0.74) RORCOSBPOSBP2USP2LMNA
SCHEMBL24085650 0.88 GRIN1 (0.76) RORCOSBPOSBP2USP2LMNA
SCHEMBL22446752 0.88 GRIN1 (0.76) RORCOSBPOSBP2USP2LMNA
SCHEMBL27507701 0.88 OSBP (0.57) RORCOSBPOSBP2USP2LMNA
SCHEMBL16713993 0.88 OSBP (0.57) RORCOSBPOSBP2USP2LMNA
SCHEMBL27507702 0.88 OSBP (0.57) RORCOSBPOSBP2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856202-A Method for determining antistreptolysin O antibody ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-01-05 — — US claimed
US-5856202-A Method for determining antistreptolysin O antibody ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-01-05 — — US disclosed
Send feedback