Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 8/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339904 | 0.99 | MAPK11 (0.45) | MAPK11MAPK14CNR2CNR1CTSS | |
| SCHEMBL20588999 | 0.80 | CTSS (0.50) | CTSSKMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8338299 | 0.77 | SMYD3 (0.47) | MAPK11MAPK14CNR2CNR1HPGDS | |
| SCHEMBL24072345 | 0.76 | KMT2A (0.61) | CNR1KMT2AL3MBTL1RAB9A | |
| SCHEMBL22338792 | 0.76 | KMT2A (0.61) | CNR1KMT2AL3MBTL1RAB9A | |
| SCHEMBL21162774 | 0.76 | F2RL1 (0.68) | F2RL1 | |
| SCHEMBL21162958 | 0.76 | F2RL1 (0.68) | F2RL1 | |
| SCHEMBL24076112 | 0.75 | KMT2A (0.59) | KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL31028315 | 0.75 | KMT2A (0.45) | KMT2AL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL8336585 | 0.75 | F2RL1 (0.66) | CNR2CNR1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |