Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 11/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336645 | 0.77 | MAPK11 (0.47) | CNR2CNR1MAPK11MAPK14HPGDS | |
| SCHEMBL8339904 | 0.75 | MAPK11 (0.45) | CNR2CNR1MAPK11MAPK14HPGDS | |
| SCHEMBL31028374 | 0.75 | SMYD3 (0.42) | SMYD3CNR2CNR1HPGDS | |
| SCHEMBL8334677 | 0.74 | LONP1 (0.63) | CNR2CNR1 | |
| SCHEMBL8339907 | 0.74 | CNR2 (0.54) | CNR2CNR1MAPK11MAPK14 | |
| SCHEMBL8337500 | 0.74 | CTSK (0.53) | CNR2CNR1MAPK11MAPK14HPGDS | |
| SCHEMBL8337771 | 0.72 | CTSK (0.51) | CNR2CNR1MAPK11MAPK14HPGDS | |
| SCHEMBL28581983 | 0.72 | SMYD3 (0.40) | SMYD3CNR2CNR1HPGDS | |
| SCHEMBL21162958 | 0.71 | F2RL1 (0.68) | — | |
| SCHEMBL21162774 | 0.71 | F2RL1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |