Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.63 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497486 | 0.78 | KDM4E (0.68) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL12256865 | 0.78 | — | — | |
| Pyrazinoic Acid SCHEMBL23757 | 0.78 | — | — | |
| Pyrazinoic Acid SCHEMBL29651929 | 0.78 | — | — | |
| SCHEMBL27791569 | 0.78 | KDM4E (0.55) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL21585664 | 0.77 | ADORA3 (0.53) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| SCHEMBL5796700 | 0.77 | KDM4E (0.50) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL9478203 | 0.76 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL623119 | 0.76 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL8341710 | 0.76 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11209351-A | — | — | None | — | — | JP | disclosed |
| US-9012637-B2 | Substituted pyrazinyl acrylic acid compounds for the inhibition of pask | BIOENERGENIX, LLC (US) | 2015-04-21 | — | — | US | disclosed |
| JP-H11209351-A | 2-PYRAZINYL-2-PROPENOIC ACID DERIVATIVE AND BACTERICIDAL AGENT FOR AGRICULTURE AND HORTICULTURE | KUREHA CHEM IND CO LTD | 1999-08-03 | — | — | JP | disclosed |
| US-4058611-A | PYRAZINYL, BILHARZIASIS, AMOEBIASIS | RHONE-POULENC INDUSTRIES (FR) | 1977-11-15 | — | — | US | disclosed |