Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719727 | 0.84 | SIGMAR1 (0.46) | SIGMAR1MEN1KMT2ANPC1TRPV1 | |
| SCHEMBL6716960 | 0.78 | KMT2A (0.60) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL6720634 | 0.78 | MEN1 (0.51) | SIGMAR1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL6725035 | 0.76 | SIGMAR1 (0.62) | SIGMAR1MEN1KMT2AMAPT | |
| SCHEMBL6719248 | 0.76 | SIGMAR1 (0.50) | SIGMAR1MEN1KMT2ANPC1MAPT | |
| SCHEMBL6720746 | 0.76 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7646944 | 0.75 | MEN1 (0.42) | SIGMAR1MEN1KMT2ANPC1MAPT | |
| SCHEMBL6727972 | 0.75 | KMT2A (0.49) | MEN1KMT2ANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL7410846 | 0.75 | SIGMAR1 (0.60) | SIGMAR1MEN1KMT2AMAPT | |
| SCHEMBL8191439 | 0.75 | SIGMAR1 (0.46) | SIGMAR1MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | claimed |