Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727972 | 0.91 | KMT2A (0.49) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6720855 | 0.89 | SIGMAR1 (0.44) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9115127 | 0.79 | SIGMAR1 (0.49) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6724187 | 0.77 | MEN1 (0.46) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL8337122 | 0.75 | SIGMAR1 (0.49) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6724190 | 0.75 | SIGMAR1 (0.62) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6724380 | 0.75 | MEN1 (0.41) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6724109 | 0.75 | SIGMAR1 (0.52) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6721320 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7415149 | 0.74 | SIGMAR1 (0.60) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517852-B1 | TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS | OREGON STATE (US) | 2002-07-10 | — | — | EP | disclosed |