Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | OTC | P00480 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976071 | 0.83 | GRM4 (0.52) | FDPSGRM4ALDH1A1PDE3ALMNA | |
| SCHEMBL11746955 | 0.79 | FDPS (0.43) | FDPSGRM4KDM4EMMP2THRB | |
| SCHEMBL11474902 | 0.75 | GRM4 (0.42) | FDPSGRM4KDM4EMMP2THRB | |
| SCHEMBL2510162 | 0.75 | — | — | |
| SCHEMBL1757439 | 0.75 | GRM4 (0.42) | FDPSGRM4KDM4EMMP2THRB | |
| SCHEMBL3170882 | 0.71 | FDPS (0.50) | FDPSGRM4PDE3ALMNAADRB3 | |
| SCHEMBL970448 | 0.71 | — | — | |
| SCHEMBL10784249 | 0.69 | KDM4E (0.39) | FDPSGRM4KDM4EMMP2THRB | |
| SCHEMBL249600 | 0.69 | KDM4E (0.39) | FDPSGRM4KDM4EMMP2THRB | |
| Hydrochloric Acid SCHEMBL9329345 | 0.69 | FDPS (0.48) | FDPSGRM4PDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802919-A4 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL INC (US) | 1999-08-18 | — | — | EP | disclosed |
| EP-0802919-A1 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995033757-A1 | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1995-12-14 | — | — | WO | disclosed |
| EP-0006659-B1 | COMPOSITIONS USEFUL IN THE PREPARATION OF STABILIZED RADIOGRAPHIC SCANNING AGENTS, A METHOD OF PREPARING THEM AND THE USE OF STANNOUS GENTISILATE AS STABILIZER IN THESE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4234562-A | WITH TECHNETIUM-99, A STANNOUS, FERROUS OR CHROMOUS CHLORIDE OR SULFATE, AN ORGANIC PHOSPHONIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-11-18 | — | — | US | disclosed |