SCHEMBL1757439

SCHEMBL1757439

NC(CP(=O)(O)O)(CP(=O)(O)O)C(N)(CP(=O)(O)O)CP(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.42
KDM4E B2RXH2 1/20 0.39
MMP2 P08253 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FDPS P14324 5/20 0.38
ALDH1A1 P00352 1/20 0.38
TYMS P04818 1/20 0.35
LMNA P02545 3/20 0.35
BLM P54132 2/20 0.35
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
ANPEP P15144 1/20 0.35
ERAP2 Q6P179 1/20 0.35
OTC P00480 1/20 0.35
LAP3 P28838 1/20 0.33
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2510162 0.80
SCHEMBL11474902 0.80 GRM4 (0.42) GRM4KDM4EMMP2THRBMAPK1
SCHEMBL11746955 0.78 FDPS (0.43) GRM4KDM4EMMP2THRBMAPK1
SCHEMBL970448 0.75
SCHEMBL8337169 0.75 FDPS (0.41) GRM4KDM4EMMP2THRBMAPK1
SCHEMBL10881796 0.73
SCHEMBL6659016 0.72 KDM4E (0.44) GRM4KDM4EMMP2THRBMAPK1
SCHEMBL8754504 0.71 FDPS (0.41) GRM4FDPSLAP3
SCHEMBL1378555 0.71 FDPS (0.41) GRM4FDPSLAP3
SCHEMBL11785300 0.71 FDPS (0.41) GRM4FDPSTYMSLMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9453117-B2 Triazine compounds containing phosphorous as flame retardants J.M. HUBER CORPORATION (US) 2016-09-27 US disclosed
US-20160053088-A1 Triazine Compounds Containing Phosphorous as Flame Retardants HUBER CORP J M (US) 2016-02-25 US disclosed
US-9200122-B2 Triazine compounds containing phosphorous as flame retardants J. M. HUBER CORPORATION (US) 2015-12-01 US disclosed
US-20140364570-A1 TRIAZINE COMPOUNDS CONTAINING PHOSPHOROUS AS FLAME RETARDANTS CATENA ADDITIVES GMBH & CO. KG 2014-12-11 US disclosed
US-8754154-B2 Triazine compounds containing phosphorous as flame retardants CATENA ADDITIVES GMBH & CO. KG (DE) 2014-06-17 US disclosed
EP-1523474-B2 CRYSTALLINE FORMS OF IMIDOALKANPERCARBOXYLIC ACIDS SOLVAY SPECIALTY POLYMERS IT (IT) 2012-12-19 EP disclosed
US-20110245383-A1 TRIAZINE COMPOUNDS CONTAINING PHOSPHOROUS AS FLAME RETARDANTS J.M. HUBER CORPORATION 2011-10-06 US disclosed
US-7943657-B2 bleach or a disinfectant composition comprising an imido-alkanpercarboxylic acid SOLVAY SOLEXIS S.P.A. (IT) 2011-05-17 US disclosed
EP-1523474-B1 CRYSTALLINE FORMS OF IMIDOALKANPERCARBOXYLIC ACIDS SOLVAY SOLEXIS SPA (IT) 2009-07-01 EP disclosed
US-7468387-B2 Crystalline forms of imidoalkanpercarboxylic acids SOLVAY SOLEXIS S.P.A. (IT) 2008-12-23 US disclosed
US-6083403-A METAL SURFACES NALCO CHEMICAL COMPANY (US) 2000-07-04 US disclosed
US-5703245-A HEATING SUSPENSION OF IMIDO ACIDS TO MELTING, SEPARATION OF ORGANIC PHASE AUSIMONT, S.P.A. (IT) 1997-12-30 US disclosed
EP-0780374-A1 Process for reducing water and polar impurities in imido-alkanpercarboxylic acids AUSIMONT S.p.A. (IT) 1997-06-25 EP disclosed
WO-1992020620-A1 METHOD FOR CATALYTIC PRODUCTION OF HYDROGEN PEROXIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-26 WO disclosed
US-5135731-A Method for catalytic production of hydrogen peroxide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-04 US disclosed
US-4248633-A Universal copper-plating solution U.S. PHILIPS CORPORATION (US) 1981-02-03 US disclosed
US-4164574-A Use of polyquaternary ammonium methylene phosphonates as microbiocides PETROLITE CORPORATION (US) 1979-08-14 US disclosed
US-4084950-A SCALE INHIBITION, CHELATION PETROLITE CORPORATION (US) 1978-04-18 US disclosed
US-4075243-A ANTISCALING, CHELATION, BACTERICIDES PETROLITE CORPORATION (US) 1978-02-21 US disclosed
US-3966630-A Use of polyquaternary ammonium methylene phosphonates in chelating or scale inhibition PETROLITE CORPORATION (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160053088-A1 Triazine Compounds Containing Phosphorous as Flame Retardants PFAS, TAF11, PUF60 GRM4 1290/4885KDM4E 1905/4885MMP2 4377/4885
US-20110245383-A1 TRIAZINE COMPOUNDS CONTAINING PHOSPHOROUS AS FLAME RETARDANTS AP2A2, P2RX2, AP2M1 GRM4 461/4885KDM4E 4381/4885MMP2 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.