Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334301 | 0.87 | METAP1 (0.49) | METAP1NPSR1NPC1MAPTRAB9A | |
| SCHEMBL8338056 | 0.82 | METAP1 (0.48) | METAP1NPSR1NPC1RAB9AKDM4E | |
| SCHEMBL7965613 | 0.80 | CYP2C9 (0.55) | METAP1NPSR1KDM4ERXFP1ADORA3 | |
| SCHEMBL8336808 | 0.78 | NPSR1 (0.46) | METAP1NPSR1NPC1MAPTRAB9A | |
| SCHEMBL8335864 | 0.78 | CBFB (0.46) | METAP1NPSR1KDM4EKMT2AMEN1 | |
| SCHEMBL8333690 | 0.78 | CBFB (0.46) | METAP1NPSR1KDM4ELMNARXFP1 | |
| SCHEMBL8333603 | 0.78 | CCR1 (0.51) | METAP1NPSR1NPC1MAPTRAB9A | |
| SCHEMBL8334580 | 0.78 | NPC1 (0.47) | METAP1NPSR1NPC1MAPTRAB9A | |
| SCHEMBL8336614 | 0.78 | KDM4E (0.54) | METAP1NPSR1MAPTKDM4EADORA3 | |
| SCHEMBL13730584 | 0.74 | CCR1 (0.55) | METAP1NPSR1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |