Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CBFB | Q13951 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965613 | 0.85 | CYP2C9 (0.55) | PKMSMN1; SMN2CBFBKDM4ENPSR1 | |
| SCHEMBL8338056 | 0.84 | METAP1 (0.48) | NPC1RAB9ACBFBKDM4ENPSR1 | |
| SCHEMBL8335315 | 0.84 | ADORA3 (0.45) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL8333690 | 0.83 | CBFB (0.46) | CBFBKDM4ENPSR1LMNACYP2C9 | |
| SCHEMBL8335864 | 0.83 | CBFB (0.46) | CBFBKDM4ENPSR1LMNAMETAP2 | |
| SCHEMBL8336808 | 0.83 | NPSR1 (0.46) | NPC1PKMRAB9ACBFBKDM4E | |
| SCHEMBL8333603 | 0.83 | CCR1 (0.51) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8336614 | 0.80 | KDM4E (0.54) | KDM4ENPSR1MAPTCYP2C9CYP3A4 | |
| SCHEMBL8337237 | 0.78 | METAP1 (0.52) | NPC1RAB9AL3MBTL1KDM4ENPSR1 | |
| SCHEMBL30210345 | 0.74 | KDM4E (0.51) | NPC1TP53PKMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |