Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 11/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15308552 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL14944839 | 0.79 | KDM5A (0.57) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL868479 | 0.79 | KDM4C (0.52) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL7082287 | 0.79 | KDM4C (0.43) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL6445581 | 0.79 | KDM4C (0.43) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL16510980 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL31198188 | 0.77 | KDM4C (0.50) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL8415760 | 0.77 | KDM4C (0.42) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL16213831 | 0.77 | LTA4H (0.49) | ALDH1A1KDM5AKDM4CKDM4APHF8 | |
| SCHEMBL7342338 | 0.77 | EPHX2 (0.49) | KDM5AKDM4CKDM4APHF8KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524863-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524863-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| US-7157470-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157470-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| WO-2004041776-A2 | SULFONYLAMINOVALEROLAC TAMS AND DERIVATIVES THEREOF AS FACTOR Xa INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-21 | — | — | WO | disclosed |