Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364359 | 0.95 | ALDH1A1 (0.55) | PTPN11ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL10592254 | 0.87 | PTPN11 (0.66) | PTPN11ALDH1A1TDP1L3MBTL1S1PR3 | |
| SCHEMBL8337247 | 0.85 | MEN1 (0.65) | PTPN11ALDH1A1TDP1L3MBTL1S1PR3 | |
| SCHEMBL3385153 | 0.84 | TSHR (0.50) | ALDH1A1MAPTMEN1LMNAHTR2B | |
| SCHEMBL8154031 | 0.84 | CYP3A4 (0.49) | PTPN11ALDH1A1S1PR3MAPTMEN1 | |
| SCHEMBL20472214 | 0.84 | MEN1 (0.51) | PTPN11ALDH1A1S1PR3MAPTMEN1 | |
| SCHEMBL20472402 | 0.84 | PTPN11 (0.51) | PTPN11ALDH1A1TDP1S1PR3MAPT | |
| SCHEMBL1153890 | 0.83 | GAA (0.60) | PTPN11ALDH1A1TDP1L3MBTL1S1PR3 | |
| SCHEMBL11370707 | 0.83 | LMNA (0.49) | ALDH1A1MAPTLMNAHTR2BHPGD | |
| SCHEMBL8778447 | 0.82 | MEN1 (0.51) | PTPN11ALDH1A1S1PR3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278680-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4207341-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER-MANNHEIM GMBH (DE) | 1980-06-10 | — | — | US | disclosed |