Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.60 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 3/20 | 0.48 |
| ▸ | ACACA | Q13085 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334717 | 0.85 | FFAR4 (0.58) | FFAR1MMP12MMP13SRD5A2FFAR4 | |
| SCHEMBL5926621 | 0.82 | FFAR1 (0.90) | FFAR1MMP12MMP13SRD5A2FFAR4 | |
| SCHEMBL691726 | 0.81 | ALDH1A1 (0.59) | FFAR1 | |
| SCHEMBL5927538 | 0.79 | FFAR1 (0.64) | FFAR1MMP12MMP13SRD5A2FFAR4 | |
| SCHEMBL10416274 | 0.79 | ALDH1A1 (0.62) | FFAR1 | |
| SCHEMBL8337882 | 0.78 | FFAR4 (0.53) | FFAR1MMP12MMP13FFAR4PLAAT3 | |
| SCHEMBL10672259 | 0.77 | FFAR1 (0.74) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL2774842 | 0.76 | FFAR1 (1.00) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL28835314 | 0.76 | FFAR1 (0.79) | FFAR1SRD5A2FFAR4PLAAT3PLAAT5 | |
| SCHEMBL8337858 | 0.76 | SLC13A5 (0.56) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |