Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334717 | 0.93 | FFAR4 (0.58) | FFAR4PTGS2MMP12MMP13FFAR1 | |
| SCHEMBL3992963 | 0.79 | FFAR4 (0.78) | FFAR4FFAR1 | |
| SCHEMBL8337256 | 0.78 | FFAR1 (0.60) | FFAR4MMP12MMP13FFAR1PLAAT3 | |
| SCHEMBL3994081 | 0.78 | FFAR4 (0.60) | FFAR4PTGS2FFAR1BRD4SLC13A5 | |
| SCHEMBL6998595 | 0.77 | HDAC1 (0.60) | ALDH1A1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7236617 | 0.73 | SLC13A5 (0.62) | FFAR4FFAR1SLC13A5PPARGPPARA | |
| SCHEMBL10416276 | 0.72 | ALOX5 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL3998350 | 0.71 | PTGS2 (0.58) | FFAR4PTGS2FFAR1BRD4KMT2A | |
| Bicarbonate SCHEMBL28250947 | 0.71 | NCOA1 (0.65) | FFAR4PTGS2FFAR1BRD4 | |
| Alanine SCHEMBL3995410 | 0.71 | NCOA1 (0.57) | FFAR4PTGS2FFAR1BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |