Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273874 | 0.83 | KDM4E (0.64) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL13480552 | 0.81 | EPHX1 (0.77) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| Hydrochloric Acid SCHEMBL9438292 | 0.81 | KDM4E (0.62) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL6720679 | 0.80 | ALDH1A1 (0.55) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL3077490 | 0.80 | KDM4E (0.60) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL7169906 | 0.76 | EPHX1 (0.53) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL15937962 | 0.75 | POLB (0.52) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL27426666 | 0.74 | ALDH1A1 (0.48) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL27429897 | 0.74 | ALDH1A1 (0.48) | EPHX1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL11632357 | 0.74 | HPGD (0.49) | EPHX1ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018465-A9 | BENZONAPHTHYRIDINES WITH PDE 3/4 INHIBITING ACTIVITY | ALTANA PHARMA AG (DE) | 2005-09-15 | — | — | WO | disclosed |