SCHEMBL8337452

SCHEMBL8337452

CCCCCCOC(O)(O)CCCCC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 1/20 0.42
CES1 P23141 1/20 0.42
FDPS P14324 8/20 0.42
GGPS1 O95749 5/20 0.42
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
LPAR3 Q9UBY5 3/20 0.39
LPAR1 Q92633 2/20 0.39
LPAR2 Q9HBW0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3167747 1.00 SMPD1 (0.42) SMPD1CES1FDPSGGPS1MEN1
SCHEMBL2302580 0.93 FDPS (0.40) SMPD1CES1FDPSGGPS1
SCHEMBL6157736 0.93 CES1 (0.39) SMPD1CES1FDPSGGPS1MEN1
SCHEMBL3181748 0.89 LPAR3 (0.49) LPAR3LPAR1LPAR2
SCHEMBL27948536 0.88 FDPS (0.40) SMPD1CES1FDPSGGPS1
Bicarbonate SCHEMBL14631950 0.85 NAAA (0.39)
SCHEMBL6537548 0.82 SMPD1 (0.52) SMPD1CES1FDPSGGPS1MEN1
SCHEMBL1395569 0.81 FDPS (0.41) SMPD1FDPSGGPS1MEN1KMT2A
SCHEMBL4318571 0.81 TSHR (0.37) SMPD1CES1FDPSGGPS1
SCHEMBL27948565 0.81 SMPD1 (0.32) SMPD1CES1FDPSGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874651-A STEAM CRACKING HEAVY BY-PRODUCT STREAM OF 1,6-HEXANEDIOL PRODUCTION TO HYDROLYSE AND FORM ISOLATABLE BY-PRODUCTS; LESS BY-PRODUCT WASTE STREAM BASF CORPORATION (US) 1999-02-23 US disclosed
US-5855816-A TREATED WITH A BLEND OF WATER AND DISTILLATION BOTTOMS, WHICH BOTTOMS ARE LIQUID AT ABOUT 60.DEGREE. C. OR LESS AND ARE OBTAINED FROM PRODUCTION OF 1,6 HEXANEDIOL. BASF CORPORATION (US) 1999-01-05 US disclosed
EP-0292772-B1 Polyether-polycarbonate diols, their preparation and their use as starting products for polyurethanes BAYER AG (DE) 1993-12-08 EP disclosed
US-5237113-A Preparation of haloalcohols BASF ALTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
EP-0266544-B1 PROCESS FOR THE PREPARATION OF HALOGENATED ALCOHOLS BASF Aktiengesellschaft (DE) 1990-12-27 EP disclosed
US-4808691-A FOR POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
EP-0292772-A2 Polyether-polycarbonate diols, their preparation and their use as starting products for polyurethanes BAYER AG (DE) 1988-11-30 EP disclosed
EP-0266544-A1 Process for the preparation of halogenated alcohols BASF Aktiengesellschaft (DE) 1988-05-11 EP disclosed