SCHEMBL8337464

SCHEMBL8337464

CC(C)(C)NN(Cc1ccc(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 3/20 0.43
TSHR P16473 2/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
NR1H4 Q96RI1 4/20 0.41
HTT P42858 2/20 0.40
NR1I2 O75469 1/20 0.40
CYP2C9 P11712 1/20 0.40
MIF P14174 1/20 0.40
TYR P14679 1/20 0.40
ALOX15 P16050 1/20 0.40
NFE2L2 Q16236 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 2/20 0.39
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3323146 0.77 AKT1 (0.50) ALDH1A1LMNAKMT2AMEN1HTT
SCHEMBL7792132 0.76 HSD17B10 (0.61) GAAALDH1A1LMNATSHRHSP90AA1
SCHEMBL3408135 0.74 ALDH1A1 (0.70) GAAALDH1A1LMNATSHRHSP90AA1
SCHEMBL29572639 0.74 ALDH1A1 (0.70) GAAALDH1A1LMNATSHRHSP90AA1
SCHEMBL9817034 0.71 ALDH1A1 (0.52) GAAALDH1A1LMNATSHRKMT2A
SCHEMBL1854630 0.70 ALDH1A1 (0.55) GAAALDH1A1LMNATSHRHSP90AA1
SCHEMBL1537791 0.70 RXRA (0.53) GAAALDH1A1LMNAHSP90AA1HSP90AB1
SCHEMBL490455 0.70 GAA (0.49) GAAALDH1A1LMNAHSP90AA1HSP90AB1
SCHEMBL2919862 0.69 ALDH1A1 (0.59) GAAALDH1A1LMNATSHRHSP90AA1
SCHEMBL7199857 0.69 ALDH1A1 (0.59) GAAALDH1A1LMNATSHRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP disclosed
WO-1993024938-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024935-A1 TELEPHONE CABLES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-12-09 WO disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
EP-0306729-B1 POLYMER BOUND ANTIOXIDANT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
US-4857596-A Polymer bound antioxidant stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed
EP-0306729-A1 Polymer bound antioxidant stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-15 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed