Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4603178 | 0.78 | SLC18A3 (0.41) | SLC18A3ESR2MEN1KMT2AKDM1A | |
| SCHEMBL5779590 | 0.76 | SLC18A3 (0.42) | SLC18A3ESR2MEN1KMT2AHTT | |
| SCHEMBL12558658 | 0.74 | ESR2 (0.39) | ESR2MEN1KMT2AKDM1AESR1 | |
| SCHEMBL19104467 | 0.73 | TDP1 (0.50) | SLC18A3ESR2MEN1KMT2AKDM1A | |
| SCHEMBL17395605 | 0.73 | TDP1 (0.50) | SLC18A3ESR2MEN1KMT2AKDM1A | |
| SCHEMBL6042249 | 0.72 | ACHE (0.56) | SLC18A3HTT | |
| SCHEMBL6953373 | 0.72 | MEN1 (0.41) | SLC18A3MEN1KMT2AHTT | |
| SCHEMBL10486574 | 0.70 | ESR2 (0.47) | SLC18A3ESR2MEN1KMT2AKDM1A | |
| SCHEMBL16883880 | 0.70 | ESR2 (0.47) | SLC18A3ESR2MEN1KMT2AKDM1A | |
| SCHEMBL27454940 | 0.69 | MEN1 (0.41) | SLC18A3MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089903-A9 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER LAMBERT CO (US) | 2005-10-27 | — | — | WO | disclosed |