Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290394 | 0.72 | MEN1 (0.52) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL13479684 | 0.70 | MAPT (0.78) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL13855610 | 0.67 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL3895454 | 0.67 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL3895459 | 0.67 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL13766507 | 0.67 | CISD1 (0.44) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL8334697 | 0.67 | KMT2A (0.53) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL14133154 | 0.65 | KMT2A (0.68) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL3893314 | 0.64 | MAPT (0.69) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL3893308 | 0.64 | MAPT (0.69) | KMT2AMAPTMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |