Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338964 | 0.84 | ALDH1A1 (0.42) | TRPV1ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL24574913 | 0.81 | CA12 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8342672 | 0.80 | ALDH1A1 (0.43) | TRPV1ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL10770150 | 0.79 | MEN1 (0.50) | POLBMAPTKDM4EHPGDKMT2A | |
| SCHEMBL3990479 | 0.79 | HTT (0.49) | TRPV1ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL8341123 | 0.77 | NAMPT (0.43) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL11737069 | 0.75 | MDM4 (0.63) | TRPV1ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL8342447 | 0.74 | ABCC1 (0.53) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL24574909 | 0.74 | CA12 (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11408752 | 0.74 | MAPT (0.62) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719320-A | 1,5-BIS(3,3-DIALKYLUREIDO)NAPHTHALENE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | claimed |
| US-5892111-A | ALKYL-SUBSTITUTED M-BIS/DIMETHYLUREIDO/BENZENES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5719320-A | 1,5-BIS(3,3-DIALKYLUREIDO)NAPHTHALENE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |