Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342672 | 0.88 | ALDH1A1 (0.43) | EPHX1ALDH1A1POLBGAALMNA | |
| SCHEMBL8339629 | 0.81 | NPSR1 (0.50) | EPHX1ALDH1A1POLBGAAKMT2A | |
| SCHEMBL8340991 | 0.80 | HDAC3 (0.48) | EPHX1ALDH1A1POLBGAAKMT2A | |
| SCHEMBL10595774 | 0.78 | NAMPT (0.53) | NAMPTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL8339328 | 0.78 | SHMT2 (0.55) | EPHX1ALDH1A1POLBGAAKMT2A | |
| SCHEMBL8338481 | 0.77 | CA12 (0.49) | ALDH1A1POLBGAALMNAKDM4E | |
| SCHEMBL8335814 | 0.76 | NPSR1 (0.46) | EPHX1ALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL8338964 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBGAALMNAKDM4E | |
| SCHEMBL8342447 | 0.74 | ABCC1 (0.53) | EPHX1ALDH1A1POLBGAALMNA | |
| SCHEMBL13984133 | 0.73 | EPHX1 (0.58) | EPHX1ALDH1A1GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719320-A | 1,5-BIS(3,3-DIALKYLUREIDO)NAPHTHALENE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | claimed |
| US-5892111-A | ALKYL-SUBSTITUTED M-BIS/DIMETHYLUREIDO/BENZENES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5719320-A | 1,5-BIS(3,3-DIALKYLUREIDO)NAPHTHALENE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |