Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299560 | 0.86 | HPGD (0.64) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8104626 | 0.82 | ALDH1A1 (0.49) | HPGDALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4122451 | 0.81 | HPGD (0.58) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8844957 | 0.81 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1300023 | 0.80 | HPGD (1.00) | HPGD | |
| SCHEMBL1300025 | 0.80 | HPGD (1.00) | HPGD | |
| SCHEMBL4119494 | 0.80 | MEN1 (0.58) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29963406 | 0.80 | MEN1 (0.65) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1300352 | 0.79 | NFE2L2 (0.61) | HPGDALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL4021594 | 0.78 | MEN1 (0.67) | HPGDALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007693-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |