Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308826 | 0.93 | FYN (0.56) | FYNMAOBPOLBGAARECQL | |
| SCHEMBL4386820 | 0.92 | MAOB (0.64) | FYNMAOBPOLBGAARECQL | |
| SCHEMBL3693339 | 0.89 | MAOB (0.67) | FYNMAOBPOLBGAARECQL | |
| SCHEMBL3813200 | 0.86 | MAOB (0.69) | MAOBPOLBGAAHPGDMEN1 | |
| SCHEMBL18121551 | 0.86 | MAOB (0.57) | FYNMAOBPOLBGAARECQL | |
| SCHEMBL9622952 | 0.86 | MAOB (0.69) | MAOBPOLBGAAHPGDMEN1 | |
| SCHEMBL2524920 | 0.84 | POLB (0.62) | FYNMAOBPOLBGAAHPGD | |
| SCHEMBL30957832 | 0.84 | POLB (0.62) | FYNMAOBPOLBGAAHPGD | |
| SCHEMBL13846509 | 0.84 | MAPT (0.49) | FYNGAAHPGDMEN1KMT2A | |
| SCHEMBL12477879 | 0.83 | APP (0.61) | FYNMAOBPOLBGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024060-A2 | METALLOPROTEINASE INHIBITORS AND INTERMEDIATES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |