Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693339 | 0.98 | MAOB (0.67) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL3813200 | 0.94 | MAOB (0.69) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL9622952 | 0.94 | MAOB (0.69) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL18121551 | 0.94 | MAOB (0.57) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL8338706 | 0.92 | FYN (0.61) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL2524920 | 0.92 | POLB (0.62) | MAOBPOLBALOX5MEN1KMT2A | |
| SCHEMBL30957832 | 0.92 | POLB (0.62) | MAOBPOLBALOX5MEN1KMT2A | |
| SCHEMBL12477879 | 0.91 | APP (0.61) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL9538855 | 0.90 | MAOB (0.53) | MAOBPOLBALOX5PTGS1PTGS2 | |
| SCHEMBL4808985 | 0.90 | MAOB (0.53) | MAOBPOLBALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023974-B2 | Ester group-containing tetracarboxylic acid dianhydride, novel polyesterimide precursor derived therefrom, and polyesterimide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-20090306329-A1 | NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306329-A1 | NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE | NOTUM, WEE2, THEM6 | MAOB 4536/4885POLB 3267/4885ALOX5 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.