Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339881 | 0.94 | CYP3A4 (0.32) | — | |
| SCHEMBL8340345 | 0.93 | ALDH1A1 (0.33) | — | |
| SCHEMBL8335550 | 0.92 | ALDH1A1 (0.34) | — | |
| SCHEMBL8338340 | 0.92 | MEN1 (0.31) | KMT2AMEN1MAPK1HTT | |
| SCHEMBL8337203 | 0.89 | — | — | |
| SCHEMBL8339030 | 0.89 | MEN1 (0.32) | KMT2AMEN1MAPK1HTT | |
| SCHEMBL8341391 | 0.88 | GAA (0.38) | KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL8341299 | 0.88 | GAA (0.38) | KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL8338585 | 0.87 | MEN1 (0.32) | KMT2AMEN1MAPK1HTT | |
| SCHEMBL8339552 | 0.85 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |