Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15655148 | 0.88 | RAB9A (0.68) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL981341 | 0.87 | SMN1; SMN2 (0.71) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL13883779 | 0.85 | SMN1; SMN2 (0.70) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL8343878 | 0.84 | PPARA (0.55) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL892234 | 0.84 | RAB9A (1.00) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL289112 | 0.83 | SMN1; SMN2 (0.93) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL8867051 | 0.83 | RAB9A (0.79) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL2011167 | 0.83 | RAB9A (0.79) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL1327631 | 0.82 | SMN1; SMN2 (1.00) | RAB9AKDM4EGAASMN1; SMN2NPC1 | |
| SCHEMBL3368828 | 0.82 | CDC7 (0.70) | KDM4EGAANPC1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |