Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336564 | 0.86 | HSD17B10 (0.49) | CNR2HSD17B10ALDH1A1HSD17B1LIG1 | |
| SCHEMBL8335747 | 0.83 | HSD17B10 (0.57) | HSD17B10ALDH1A1HSD17B1HSD17B2NPC1 | |
| SCHEMBL8771736 | 0.83 | HSD17B10 (0.62) | CNR2CNR1CA12CA9HSD17B10 | |
| SCHEMBL8340975 | 0.83 | HSD17B10 (0.61) | HSD17B10ALDH1A1HSD17B1HSD17B2LIG1 | |
| SCHEMBL14134424 | 0.81 | CNR2 (0.65) | CNR2CNR1ALDH1A1HTTPOLB | |
| SCHEMBL8771678 | 0.79 | CYP46A1 (0.54) | CNR2CNR1CA12CA9HSD17B10 | |
| SCHEMBL8160674 | 0.78 | ESR2 (0.48) | CNR2CNR1CA12CA9HSD17B1 | |
| SCHEMBL10954387 | 0.77 | CNR2 (0.64) | CNR2CNR1ALDH1A1KMT2AHTT | |
| SCHEMBL9244044 | 0.76 | HSD17B10 (0.66) | HSD17B10ALDH1A1HSD17B1HSD17B2LIG1 | |
| SCHEMBL8161985 | 0.76 | CNR2 (0.47) | CNR2CNR1CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |