Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244044 | 0.93 | HSD17B10 (0.66) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8338950 | 0.87 | HSD17B1 (0.56) | HSD17B10MEN1KMT2ARAB9AMAPT | |
| SCHEMBL7167629 | 0.86 | LIG1 (0.61) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL20147808 | 0.85 | MEN1 (0.62) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8339290 | 0.83 | MAPK1 (0.59) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8340721 | 0.83 | MEN1 (0.61) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8335747 | 0.83 | HSD17B10 (0.57) | HSD17B10MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8339441 | 0.83 | CNR2 (0.59) | HSD17B10KMT2ARAB9AMAPTLIG1 | |
| SCHEMBL699045 | 0.82 | HSD17B10 (0.81) | HSD17B10MEN1KMT2AMAPTALOX5 | |
| SCHEMBL8335949 | 0.81 | GSTA1 (0.58) | HSD17B10MEN1KMT2ALMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |