Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073235 | 0.89 | MEN1 (0.46) | CYP24A1VDRMEN1KMT2AALDH1A1 | |
| SCHEMBL6098372 | 0.87 | ALDH1A1 (0.48) | CYP24A1VDRMEN1KMT2AALDH1A1 | |
| SCHEMBL2340512 | 0.87 | ALDH1A1 (0.49) | CYP24A1VDRKDM4EL3MBTL1MEN1 | |
| SCHEMBL2337256 | 0.86 | REN (0.44) | KDM4EL3MBTL1MEN1KMT2APKM | |
| SCHEMBL2246161 | 0.83 | ALDH1A1 (0.49) | CYP24A1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL21618180 | 0.82 | ALDH1A1 (0.50) | CYP24A1VDRALDH1A1CA12CA1 | |
| SCHEMBL12737574 | 0.82 | ALDH1A1 (0.50) | CYP24A1VDRALDH1A1CA12CA1 | |
| SCHEMBL25311278 | 0.82 | ALDH1A1 (0.48) | CYP24A1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL27031942 | 0.81 | ALDH1A1 (0.47) | CYP24A1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL23250068 | 0.81 | ALDH1A1 (0.47) | CYP24A1L3MBTL1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089903-A9 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER LAMBERT CO (US) | 2005-10-27 | — | — | WO | disclosed |