Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoxaben SCHEMBL54432 | 0.88 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| Isoxaben SCHEMBL8539623 | 0.88 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| Isoxaben SCHEMBL9713018 | 0.87 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| Isoxaben SCHEMBL28180388 | 0.86 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL16589802 | 0.83 | TAS1R3 (0.51) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL11102585 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9713569 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL9713162 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9712899 | 0.82 | MAPK14 (0.50) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| Isoxaben SCHEMBL6428745 | 0.81 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002660-A1 | CATALYTIC ANTIBODIES FOR THE INACTIVATION OF HERBICIDES | KEINAN EHUD (IL) | 1999-01-21 | — | — | WO | disclosed |