SCHEMBL833952

SCHEMBL833952

O=Cc1ccc(SC(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
PTPRZ1 P23471 4/20 0.50
PTPN1 P18031 2/20 0.50
CYP2A6 P11509 3/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
KIF11 P52732 2/20 0.41
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
PPARG P37231 1/20 0.37
TYR P14679 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24512641 0.89 PTPRZ1 (0.46) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL6685855 0.80 PTPRZ1 (0.77) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL5057067 0.77 ALDH1A1 (0.58) ALDH1A1KDM4ECYP2A6HSD17B10ALDH5A1
SCHEMBL695549 0.77 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL5399931 0.77 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL694683 0.77 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL7810144 0.77 ALDH1A1 (0.42) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL7810141 0.77 ALDH1A1 (0.42) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL30540204 0.75 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL9110887 0.75 KIF11 (0.51) ALDH1A1KDM4ETDP1PTPRZ1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546103-A 4-Formamide oxazole compound and preparation method and application thereof 上海大学 2024-08-27 CN claimed
CN-104093709-B It is used as the imidazole derivative of aldosterone synthase inhibitors 霍夫曼-拉罗奇有限公司 2017-09-22 CN claimed
CN-104093709-A Imidazolylketone derivatives as aldosterone synthase inhibitors HOFFMANN LA ROCHE 2014-10-08 CN claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US disclosed
US-20250223301-A1 KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2025-07-10 US disclosed
EP-4499640-A1 KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF InventisBio Co., Ltd. (CN) 2025-02-05 EP disclosed
WO-2024212742-A1 GLP-1R AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF 上海研健新药研发有限公司 2024-10-17 WO disclosed
WO-2024141128-A4 STING INHIBITOR PRODRUG AND MEDICAL USE THEREOF 中国药科大学 2024-09-19 WO disclosed
CN-118546103-A 4-Formamide oxazole compound and preparation method and application thereof 上海大学 2024-08-27 CN disclosed
WO-2024141128-A2 STING INHIBITOR PRODRUG AND MEDICAL USE THEREOF 中国药科大学 2024-07-04 WO disclosed
WO-2024125629-A1 UREIC COMPOUND AND PHARMACEUTICAL USE THEREOF AS STING INHIBITOR 中国药科大学 2024-06-20 WO disclosed
EP-0294229-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-12-02 EP disclosed
CN-1030236-A NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS WELLCOME FOUND (GB) 1989-01-11 CN disclosed
EP-0294229-A2 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed
US-4588844-A Process for preparing aromatic aldehydes BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
US-4384114-A Styryl substituted Γ-lactone derivatives BAYER AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed
EP-0019713-B1 PROCESS FOR THE PREPARATION OF STYRYL-CYCLOPROPANE CARBOXYLATES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION BAYER AG (DE) 1983-02-16 EP disclosed
US-4327025-A Preparation of styryl-cyclopropane-carboxylic acid esters and intermediate therefor BAYER AKTIENGESELLSCHAFT (DE) 1982-04-27 US disclosed
EP-0019713-A1 Process for the preparation of styryl-cyclopropane carboxylates, intermediates therefor and their production BAYER AG (DE) 1980-12-10 EP disclosed
US-4104379-A DOPAMINERGIC ACTIVITY SMITHKLINE CORPORATION (US) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250223301-A1 KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF MAP3K19, MAP3K1, MAP3K20 ALDH1A1 4498/4885KDM4E 1816/4885TDP1 1159/4885
US-12568969-B2 Pyridine compounds for controlling invertebrate pests COX6C, CCR1, CBR3 ALDH1A1 1464/4885KDM4E 1584/4885TDP1 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.