Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839950 | 0.87 | SLC2A1 (0.60) | GSK3BMAPTKDM4EHSD17B10LMNA | |
| SCHEMBL8338958 | 0.85 | GSK3B (0.57) | GSK3BMAPTKDM4EHSD17B10TP53 | |
| SCHEMBL8342647 | 0.82 | KDM4E (0.65) | GSK3BMAPTKDM4EHSD17B10TP53 | |
| SCHEMBL840324 | 0.82 | NPC1 (0.71) | MAPTKDM4EHSD17B10TP53LMNA | |
| SCHEMBL8344605 | 0.81 | LMNA (0.52) | MAPTKDM4EHSD17B10TP53LMNA | |
| SCHEMBL6224500 | 0.81 | MAPT (0.65) | MAPTKDM4EHSD17B10TP53LMNA | |
| SCHEMBL6225759 | 0.79 | SLC2A1 (0.58) | GSK3BMAPTKDM4EHSD17B10TP53 | |
| SCHEMBL8344595 | 0.79 | GSK3B (0.54) | GSK3BMAPTKDM4EHSD17B10TP53 | |
| SCHEMBL3428361 | 0.79 | TP53 (0.50) | MAPTKDM4EHSD17B10TP53LMNA | |
| SCHEMBL30034914 | 0.78 | ALDH1A1 (0.67) | MAPTKDM4EHSD17B10TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |