Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843102 | 0.89 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL6448285 | 0.86 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5600147 | 0.83 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL5843479 | 0.79 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL16606729 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5844698 | 0.78 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL5843501 | 0.78 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5845247 | 0.77 | CRHR1 (0.44) | CRHR1 | |
| Methylene Chloride SCHEMBL5846201 | 0.77 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL5844362 | 0.77 | CRHR1 (0.67) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962479-A | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0764166-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER INC. (US) | 1997-03-26 | — | — | EP | disclosed |