Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8339730

C[N+](C)(C)CC[N+](C)(C)C.[Cl-].[Cl-]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.54
APEX1 P27695 3/20 0.61
NPSR1 Q6W5P4 1/20 0.61
CYP3A4 P08684 1/20 0.57
SLC5A7 Q9GZV3 1/20 0.57
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
LMNA P02545 3/20 0.54
NFKB1 P19838 2/20 0.54
KDM4E B2RXH2 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
PMP22 Q01453 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HRH3 Q9Y5N1 1/20 0.54
TSHR P16473 1/20 0.54
RAB9A P51151 1/20 0.54
DNM1 Q05193 6/20 0.47
BBOX1 O75936 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235599 0.94 MEN1 (0.58) APEX1NPSR1CYP3A4SLC5A7MEN1
Water SCHEMBL4489648 0.89 MEN1 (0.54) APEX1NPSR1CYP3A4SLC5A7MEN1
Iodide SCHEMBL1982646 0.89 MEN1 (0.54) APEX1NPSR1CYP3A4SLC5A7MEN1
Bromide SCHEMBL11130043 0.89 MEN1 (0.61) APEX1NPSR1CYP3A4SLC5A7MEN1
Fluoride Ion SCHEMBL1444803 0.89 MEN1 (0.54) APEX1NPSR1CYP3A4SLC5A7MEN1
SCHEMBL14754176 0.80 MEN1 (0.47) APEX1NPSR1CYP3A4SLC5A7MEN1
Hydrochloric Acid SCHEMBL4541161 0.80 APEX1 (0.77) APEX1NPSR1CYP3A4SLC5A7MEN1
Decamethonium SCHEMBL2830377 0.77 APEX1 (1.00) APEX1NPSR1CYP3A4SLC5A7MEN1
Hydrochloric Acid SCHEMBL20769541 0.77 DNM1 (0.56) APEX1NPSR1CYP3A4SLC5A7MEN1
Hydrochloric Acid SCHEMBL3679398 0.77 APEX1 (1.00) APEX1NPSR1CYP3A4SLC5A7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112028553-A Material for engineering tunnel and subway tunneling and preparation method thereof 濮阳市诚信钻采助剂有限公司 2020-12-04 CN disclosed
US-5942722-A CL-20 COATED WITH SHOCK SENSITIVITY REDUCING AGENTS TO REDUCE THE SUSCEPTIBILITY TO IMPACT AND SYMPATHETIC DETONATION ANDIMPART AN INCREASE IN HDC IMPACT VALUE WHICH IS STATISTICALLY SIGNIFICANT; USING ANIONIC AROMATIC AGENTS EASTMAN CHEMICAL COMPANY (US) 1999-08-24 US disclosed
US-5942721-A CL-20 COATED WITH SHOCK SENSITIVITY REDUCING AGENTS TO REDUCE THE SUSCEPTIBILITY TO IMPACT AND SYMPATHETIC DETONATION ANDIMPART AN INCREASE IN HDC IMPACT VALUE WHICH IS STATISTICALLY SIGNIFICANT; USING ANIONIC AROMATIC AGENTS EASTMAN CHEMICAL COMPANY (US) 1999-08-24 US disclosed
US-5936196-A 2,4,6,8,10,12-HEXANITROHEXAAZOISONURTITANE COATED WITH AMINE SHOCK SENSITIVITY REDUCING AGENT EASTMAN CHEMICAL CO. (US) 1999-08-10 US disclosed
EP-0932591-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1999-08-04 EP disclosed
EP-0898553-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1999-03-03 EP disclosed
EP-0896576-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1999-02-17 EP disclosed
EP-0896574-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1999-02-17 EP disclosed
EP-0896575-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1999-02-17 EP disclosed
US-5808234-A CYCLOTRIMETHYLENE-TRINITRAMINE EXPLOSIVE CONTAINING A SHOCK SENSITIVITY REDUCING AGENT COMPRISING TRIALKYL POLYOXYALKYLENE QUATERNARY AMMONIUM CHLORIDE EXHIBITS ANTISTATIC PROPERTIES EASTMAN CHEMICAL COMPANY (US) 1998-09-15 US disclosed
US-5801326-A Explosive formulations EASTMAN CHEMICAL COMPANY (US) 1998-09-01 US disclosed
WO-1998016485-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1998-04-23 WO disclosed
WO-1997042138-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1997-11-13 WO disclosed
WO-1997042137-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1997-11-13 WO disclosed
WO-1997042139-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1997-11-13 WO disclosed
WO-1997042140-A1 EXPLOSIVE FORMULATIONS EASTMAN CHEMICAL COMPANY (US) 1997-11-13 WO disclosed
US-5171830-A Catalytic process for the preparation of polyalkylene carbonates ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-12-15 US disclosed
US-4334022-A BY CULTIVATING IN A CULTURE MEDIUM CONTAINING AN N-METHYL COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-06-08 US disclosed
US-3954650-A Amine hardner compositions UNION CARBIDE CORPORATION (US) 1976-05-04 US disclosed