Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 1.00 |
| ▸ | GSK3A | P49840 | 5/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344915 | 0.90 | GSK3B (0.82) | GSK3BGSK3AADORA1 | |
| SCHEMBL8339138 | 0.87 | GSK3B (0.76) | GSK3BGSK3AADORA1 | |
| SCHEMBL8342571 | 0.86 | GSK3B (0.75) | GSK3BGSK3AADORA1 | |
| SCHEMBL6205301 | 0.86 | GSK3B (0.75) | GSK3BGSK3AADORA1 | |
| SCHEMBL8344731 | 0.86 | GSK3B (0.75) | GSK3BGSK3AADORA1 | |
| SCHEMBL8342553 | 0.86 | GSK3B (0.75) | GSK3BGSK3AADORA1 | |
| SCHEMBL8344464 | 0.82 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8344625 | 0.82 | GSK3B (1.00) | GSK3BGSK3A | |
| Gw784752X SCHEMBL8344352 | 0.82 | GSK3B (1.00) | GSK3BGSK3A | |
| Gw784752X SCHEMBL29534241 | 0.82 | GSK3B (1.00) | GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |