Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw784752X SCHEMBL8344352 | 1.00 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8339760 | 0.92 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8344607 | 0.91 | GSK3B (0.84) | GSK3BGSK3A | |
| SCHEMBL8343169 | 0.90 | GSK3B (0.82) | GSK3BGSK3A | |
| SCHEMBL8342451 | 0.90 | GSK3B (0.82) | GSK3BGSK3A | |
| SCHEMBL8342769 | 0.90 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8344429 | 0.90 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8344464 | 0.89 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL8339151 | 0.89 | GSK3B (0.81) | GSK3BGSK3A | |
| SCHEMBL8344582 | 0.89 | GSK3B (0.89) | GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066856-A1 | PLATFORM AND SAMPLE TYPE INDEPENDENT SINGLE SAMPLE CLASSIFIER FOR TREATMENT DECISION MAKING IN PANCREATIC DUCTAL ADENOCARCINOMA CANCER | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-02-27 | — | — | US | disclosed |
| US-12000003-B2 | Platform and sample type independent single sample classifier for treatment decision making in pancreatic ductal adenocarcinoma cancer | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-06-04 | — | — | US | disclosed |
| US-20220339154-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR GENERATING INNER EAR HAIR CELLS FOR TREATMENT OF HEARING LOSS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-10-27 | — | — | US | disclosed |
| US-20220259559-A1 | COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY UPREGULATING JAG-1 | Frequency Therapeutics, Inc. | 2022-08-18 | — | — | US | disclosed |
| US-11369607-B2 | Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| US-20220192984-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS | Frequency Therapeutics, Inc. | 2022-06-23 | — | — | US | disclosed |
| US-20220175776-A1 | COMBINATION OF CHIR99021 AND VALPROIC ACID FOR TREATING HEARING LOSS | Frequency Therapeutics, Inc. (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220170109-A1 | PURITY INDEPENDENT SUBTYPING OF TUMORS (PURIST), A PLATFORM AND SAMPLE TYPE INDEPENDENT SINGLE SAMPLE CLASSIFIER FOR TREATMENT DECISION MAKING IN PANCREATIC CANCER | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-06-02 | — | — | US | disclosed |
| US-20220160664-A1 | TAZ ACTIVATORS AND WNT AGONISTS FOR TREATING EAR DISORDERS | UNITED STATES GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| US-20220133740-A1 | VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS | Frequency Therapeutics, Inc. (US) | 2022-05-05 | — | — | US | disclosed |
| US-20220127568-A1 | COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS | Frequency Therapeutics, Inc. (US) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127568-A1 | COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY INHIBITING EPIGENETIC TARGETS | WNT3A, WNT1, MECP2 | GSK3B 92/4885GSK3A 152/4885 |
| US-20220339154-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR GENERATING INNER EAR HAIR CELLS FOR TREATMENT OF HEARING LOSS | SHH, MYOC, HES1 | GSK3B 1047/4885GSK3A 1335/4885 |
| US-20220175776-A1 | COMBINATION OF CHIR99021 AND VALPROIC ACID FOR TREATING HEARING LOSS | HES1, SHH, HDAC11 | GSK3B 678/4885GSK3A 732/4885 |
| US-20220133740-A1 | VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS | WNT3A, WNT1, WNT3 | GSK3B 42/4885GSK3A 24/4885 |
| US-20220160664-A1 | TAZ ACTIVATORS AND WNT AGONISTS FOR TREATING EAR DISORDERS | WNT1, WNT3A, CTNNB1 | GSK3B 63/4885GSK3A 66/4885 |
| US-20220259559-A1 | COMPOSITIONS AND METHODS FOR GENERATING HAIR CELLS BY UPREGULATING JAG-1 | NOTCH1, HES1, NOTCH3 | GSK3B 1102/4885GSK3A 1348/4885 |
| US-11369607-B2 | Compositions, systems, and methods for generating inner ear hair cells for treatment of hearing loss | SHH, MYOC, HES1 | GSK3B 1047/4885GSK3A 1335/4885 |
| US-20220192984-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING OTIC THERAPEUTIC AGENTS AND RELATED METHODS | OTC, EXOSC5, ENTPD5 | GSK3B 2670/4885GSK3A 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.