Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343570 | 0.84 | HDAC3 (0.62) | FFAR4S1PR1HDAC3MAPK1ADRA1A | |
| SCHEMBL4427532 | 0.80 | USP5 (0.66) | HDAC1SMN1; SMN2HDAC8HDAC6SIGMAR1 | |
| SCHEMBL6625042 | 0.80 | HSD17B10 (0.60) | FFAR4S1PR1HDAC3MAPK1ADRA1A | |
| SCHEMBL1454883 | 0.80 | FFAR4 (0.60) | FFAR4S1PR1HDAC3MAPK1ADRA1A | |
| SCHEMBL7412896 | 0.78 | RAB9A (0.50) | FFAR4SIGMAR1MEN1KMT2A | |
| SCHEMBL19599852 | 0.78 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL7616187 | 0.77 | FFAR4 (0.44) | FFAR4SMN1; SMN2SIGMAR1MEN1TP53 | |
| SCHEMBL27576554 | 0.76 | USP5 (0.49) | FFAR4SMN1; SMN2HDAC6SIGMAR1TP53 | |
| SCHEMBL7417928 | 0.76 | USP5 (0.49) | FFAR4SMN1; SMN2HDAC6SIGMAR1TP53 | |
| SCHEMBL6674717 | 0.76 | MEN1 (0.49) | SIGMAR1MEN1TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |