Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 19/20 | 0.67 |
| ▸ | MMP13 | P45452 | 16/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340262 | 1.00 | MMP12 (0.67) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL27540150 | 0.87 | MMP13 (0.70) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL4424736 | 0.87 | MMP13 (0.70) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL6350414 | 0.83 | MMP12 (0.78) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL27542526 | 0.83 | MMP12 (0.78) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL4432986 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL27540153 | 0.81 | MMP12 (1.00) | MMP12MMP13MMP2MMP3MMP9 | |
| SCHEMBL6419152 | 0.80 | MMP12 (0.66) | MMP12MMP13 | |
| SCHEMBL6413671 | 0.80 | MMP12 (0.69) | MMP12MMP13 | |
| SCHEMBL6339753 | 0.79 | MMP12 (0.79) | MMP12MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |