Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108166 | 0.80 | PKM (0.58) | PKMMAPTLMNACYP1A2POLB | |
| SCHEMBL2373276 | 0.78 | PKM (0.61) | PKMMAPTLMNACYP1A2POLB | |
| SCHEMBL1609142 | 0.75 | MAPT (0.61) | PKMMAPTLMNACYP1A2POLB | |
| SCHEMBL8340619 | 0.74 | SMN1; SMN2 (0.44) | PKMMAPTCYP1A2POLBHTT | |
| SCHEMBL4360389 | 0.74 | PTGDR2 (0.38) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8854253 | 0.74 | L3MBTL1 (0.38) | MAPTLMNAHTTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11271192 | 0.73 | MAPT (0.59) | PKMMAPTLMNACYP1A2POLB | |
| SCHEMBL4352330 | 0.73 | KDM4E (0.49) | MAPTLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10922454 | 0.72 | PKM (0.53) | PKMMAPTLMNACYP1A2POLB | |
| SCHEMBL2386652 | 0.71 | PKM (0.66) | PKMMAPTLMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885935-A | Sulfonamide herbicides | AGREVO UK LIMITED (GB) | 1999-03-23 | — | — | US | disclosed |
| EP-0625970-B1 | SULFONAMIDE HERBICIDES | AGREVO UK LTD (GB) | 1997-09-17 | — | — | EP | disclosed |
| US-5559081-A | Sulfonamide herbicides | AGREVO UK LIMITED (GB) | 1996-09-24 | — | — | US | disclosed |
| EP-0625970-A1 | SULFONAMIDE HERBICIDES. | AGREVO UK LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993009099-A2 | SULFONAMIDE HERBICIDES | AGREVO UK LIMITED (GB) | 1993-05-13 | — | — | WO | disclosed |